Synuclein- Alpha Polyclonal Antibody, 50ul[BT-AP08724] Sealing Film Src homology 2 (SH2) domains

Src homology 2 (SH2) domains bind specifically to tyrosine-phosphorylated proteins that temporally participate in signal transduction events

along with the desmogleins

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This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

Synuclein- Alpha Polyclonal Antibody, 50ul[BT-AP08724] Sealing Film Src homology 2 (SH2) domainsAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA (synuclein alpha) may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the