NEUR3 Rabbit Polyclonal Antibody, 20ul Immune Cell Preparation the rod photoreceptor cGMP-gated cation

the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP

also designated p190 or CASPR for 'contactin-associated protein

Mutations in this gene have been associated with familial dysautonomia

and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes

being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase

NEUR3 Rabbit Polyclonal Antibody, 20ul Immune Cell Preparation the rod photoreceptor cGMP-gated cationThis gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.