p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix It appears to function as

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

An important paralog of this gene is HNRNPUL2-BSCL2

GO annotations related to this gene include DNA-directed RNA polymerase activity and RNA polymerase I transcription factor binding

Transcription repressor ZNF278/PATZ is found to interact with this protein| and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein

such as colon

p53 (Acetyl Lys381) Polyclonal Antibody, 100ul Biomatrix It appears to function asTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni