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GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates This gene encodes a protein

SKU: 86895941228

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GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates This gene encodes a proteinThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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Description

This gene encodes a protein that contains a DNA-binding domain

deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium

the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation

is associated with the chromosome 9 gene encoding endoglin protein

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains

GRK2(Phospho-Tyr86) Polyclonal Antibody, 50ul Immuno Plates This gene encodes a proteinThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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