MMP-8 Polyclonal Antibody, 100ul Custom DNA Oligos This gene encodes a secreted

This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins

PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells

it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

PGBD1 belongs to the subfamily of piggyBac transposable element derived (PGBD) genes

MMP-8 Polyclonal Antibody, 100ul Custom DNA Oligos This gene encodes a secretedMMP8 encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N termini. This protein functions in the degradation of type I, II