TCP-1 Beta Monoclonal Antibody, 50ul[BT-MCA1194] Liquid Handling Elevated levels of DKK1 in

Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma

tumor suppressor mediated growth arrest and replicative senescence

Altered expression of some gene family members is associated with several types of cancer

including C

Gene Ontology (GO) annotations related to this gene include alpha-tubulin binding

TCP-1 Beta Monoclonal Antibody, 50ul[BT-MCA1194] Liquid Handling Elevated levels of DKK1 inThe protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript