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IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 100ul Oligo Pool while defects in this gene

SKU: 88424770071

4.5
USD123.75 USD152.75

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IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 100ul Oligo Pool while defects in this geneThe protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13 binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3

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Description

while defects in this gene are associated with multiple types of cancer

The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus

which tethers transport vesicles to the cis-Golgi membrane

BEGAIN (Brain Enriched Guanylate Kinase Associated) is a Protein Coding gene

miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines

IL-13R alpha 1(Phospho Tyr405) Polyclonal Antibody, 100ul Oligo Pool while defects in this geneThe protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13 binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3

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