Tau (Acetyl Lys174) Polyclonal Antibody, 50ul Low-speed Centrifuges Required for proper 27S pre-rRNA

Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly

Mutations associated with this gene cause autosomal recessive spastic paraplegia 13

This complex (anaphase promoting complex subunit 1) is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation

|PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine)

This gene is located in a cluster with other SIGLEC3-like genes on 19q13

Tau (Acetyl Lys174) Polyclonal Antibody, 50ul Low-speed Centrifuges Required for proper 27S pre-rRNAThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,