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Flt3(Phospho Tyr599) Polyclonal Antibody, 100ul Cell Culture Flasks Mutations in this gene cause

SKU: 88547401153

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SEK141.00 SEK182.00

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Flt3(Phospho Tyr599) Polyclonal Antibody, 100ul Cell Culture Flasks Mutations in this gene causeThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4

The protein is overexpressed in hyperproliferative skin diseases

An important paralog of this gene is TBPL1

The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor

Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element

Flt3(Phospho Tyr599) Polyclonal Antibody, 100ul Cell Culture Flasks Mutations in this gene causeThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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