ACBP Polyclonal Antibody, 100ul[BT-AP00147] Centrifuge Tube (Bottle) HECT domain E3 ubiquitin ligases

HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates| thus targeting specific proteins for lysosomal degradation

the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus

Mutations in this gene are associated with Doyne honeycomb retinal dystrophy

Osteoporosis is characterized by reduced bone mineral density| disrutption of bone microarchitecture| and the alteration of the amount and variety of non-collagenous proteins in bone

|PTM:Not phosphorylated

ACBP Polyclonal Antibody, 100ul[BT-AP00147] Centrifuge Tube (Bottle) HECT domain E3 ubiquitin ligasesDBI encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta carbolines and benzodiazepines, which modulate signal transduction at type A gamma aminobutyric acid receptors located in brain synapses. The protein is conserved is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic