PA21B Polyclonal Antibody, 50ul Inoculating Loops/Needles also known as serologically defined

also known as serologically defined breast cancer antigen NY-BR-1

A related pseudogene has been found on chromosome 6

Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

Mitogen-activated protein kinase kinase kinase kinase 3 activates key effectors in cell signalling

two glycosylation sites

PA21B Polyclonal Antibody, 50ul Inoculating Loops/Needles also known as serologically definedThis gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium dependent enzyme catalyzes the hydrolysis of the sn 2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs)