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Stat5b Monoclonal Antibody, 50ul Electronic Pipette WD repeat and HMG-box DNA-binding

SKU: 89040981470

4.4
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Stat5b Monoclonal Antibody, 50ul Electronic Pipette WD repeat and HMG-box DNA-bindingThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth

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Description

WD repeat and HMG-box DNA-binding protein 1encoded by WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm

Keratin 13 encoded by KRT13 is a member of the keratin gene family

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

Stat5b Monoclonal Antibody, 50ul Electronic Pipette WD repeat and HMG-box DNA-bindingThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth

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