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p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This protein is expressed at

SKU: 89290628730

4.8
SEK141.00 SEK169.00

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p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This protein is expressed atThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain| beginning with the sequence PFXYD| and containing 7 invariant and 6 highly conserved amino acids

Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands

This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion| cell morphology and cell motility

as well as histone deacetylases

p53(Phospho Ser37) Polyclonal Antibody, 100ul Peripheral Blood Separation Tube This protein is expressed atThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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