Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation PHACTR4 (phosphatase and actin regulator

PHACTR4 (phosphatase and actin regulator 4) encodes a member of the phosphatase and actin regulator (PHACTR) family

The protein encoded by this gene contains a ring finger motif| which is known to be involved in protein-protein interactions

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

This protein plays a role in regulating cell migration

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation PHACTR4 (phosphatase and actin regulatorThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a