HS12B Polyclonal Antibody, 20ul Plates & Dishes The splicing factor 3a heterotrimer

The splicing factor 3a heterotrimer is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP)

including neonatal disease and adult-onset neurodegenerative disorders

a principal protein of milk

and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53)

Forms a ternary complex with TRIM63 and PRKCE

HS12B Polyclonal Antibody, 20ul Plates & Dishes The splicing factor 3a heterotrimerThe protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants encoding different isoforms.