SHIP2(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging NF-kappa-B moves to the nucleus

NF-kappa-B moves to the nucleus and activates transcription of specific genes

Defects in this gene are a cause of Bernard-Soulier syndrome

This gene encodes a secreted

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways

Mutations in ITPR1 cause spinocerebellar ataxia type 15

SHIP2(Phospho-Tyr1135) Rabbit Polyclonal Antibody, 20ul Lentiviral Packaging NF-kappa-B moves to the nucleusThe protein encoded by this gene is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.