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Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos Component of the NF-kappa-B RelB-p52

SKU: 89991239971

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Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos Component of the NF-kappa-B RelB-p52The protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

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Description

Component of the NF-kappa-B RelB-p52 complex

ADAM17 (ADAM metallopeptidase domain 17) encodes a member of the ADAM (a disintegrin and metalloprotease domain) family

This gene and other MAGEB members are clustered on chromosome Xp22-p21

The gene is located in the chromosome 3 common eliminated region 1 (C3CER1)| a 1

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt

Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos Component of the NF-kappa-B RelB-p52The protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

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