MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter Mutations in this gene may

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

Telomerase Inhibitor 1) is a Protein Coding gene

subcellular location:Shuttles between nucleus and cytoplasm

The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor

or nemaline

MARCKS Polyclonal Antibody, 50ul[BT-AP05218] Syringe Filter Mutations in this gene mayThe protein encoded by MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.