Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit, 96T Modification Enzymes Studies of the similar gene

Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin

This protein is thought to play a role in multiple cellular processes| including tumorigenesis| neurodegeneration and apoptosis

CDKN1B encodes a cyclin-dependent kinase inhibitor

PubMed: 29244122)

through MTOR signaling pathway activation and BCL2 up-regulation (By similarity)

Rat Cop9 Signalosome Compex Subunit 1, GPS1 ELISA Kit, 96T Modification Enzymes Studies of the similar geneEssential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53 TP53, c