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A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation

The human genome contains five CD1 family genes organized in a cluster on chromosome 1

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

Alternative splicing results in multiple transcript variants and protein isoforms

UNC5B Polyclonal Antibody, 20ul Protein Research Vacuum-packed in a bag withThis gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin 1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro and anti apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.