PDE2A Polyclonal Antibody, 50ul Peptide Modification The protein encoded by this

The protein encoded by this gene belongs to the small GTPase superfamily

It contributes significantly to the pathogenesis of many characteristics of Down syndrome| including morphological features| hypotonia| and mental retardation

May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

The protein belongs to the L1P family of ribosomal proteins

This gene may play a role in malignancies and disease that involve this region

PDE2A Polyclonal Antibody, 50ul Peptide Modification The protein encoded by thisalternative products: Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,Catalytic activity: Nucleoside 3',5' cyclic phosphate + H(2)O = nucleoside 5' phosphate.,Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,Belongs to the cyclic nucleotide phosphodiesterase family.,Contains 2 GAF domains.,subunit: Homodimer.,tissue specificity: Expressed in brain and to a lesser extent in heart, placenta, lung,