PGFRL Polyclonal Antibody, 50ul Antibody Humanization p21 activated kinase

p21 activated kinase

and is related to platelet-derived growth factor

The encoded protein (CD300 molecule like family member f) is an inhibitory receptor

having been shown to have bacteriocidal and antifungal activities

Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex| leading to epilepsy| mental retardation| subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo

PGFRL Polyclonal Antibody, 50ul Antibody Humanization p21 activated kinaseThis gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non small cell lung cancers. This suggests this gene product may function as a tumor suppressor.