PHF1 Polyclonal Antibody, 50ul Enzymes Sec7 and coiled-coil domains) family
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PHF1 Polyclonal Antibody, 50ul Enzymes Sec7 and coiled-coil domains) familyPHF1 encodes a Polycomb group protein. PHD finger protein 1 is a component of a histone H3 lysine 27 (H3K27) specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. PHD finger protein 1 is also recruited to double strand breaks, and reduced protein levels results in X ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for PHF1.
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