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NT5C3 Polyclonal Antibody, 100ul Gloves This gene encodes a sodium/bile

SKU: 91450794392

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NT5C3 Polyclonal Antibody, 100ul Gloves This gene encodes a sodium/bileNT5C3A (5' nucleotidase, cytosolic IIIA) encodes a member of the 5' nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5' monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5 prime monophosphate hydrolase deficiency. Alternatively spliced transcript

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Description

This gene encodes a sodium/bile acid cotransporter

GO annotations related to this gene include cyclin-dependent protein serine/threonine kinase regulator activity

Rho guanine nucleotide exchange factor 2 may form complex with G proteins and stimulate rho-dependent signals

AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

NT5C3 Polyclonal Antibody, 100ul Gloves This gene encodes a sodium/bileNT5C3A (5' nucleotidase, cytosolic IIIA) encodes a member of the 5' nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5' monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5 prime monophosphate hydrolase deficiency. Alternatively spliced transcript

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