DMPK Polyclonal Antibody, 50ul Mini dry bath The first exon of this

The first exon of this gene is unrelated to immunoglobulin variable genes

and Familial dysautonomia

alternatively spliced transcript variants encoding a range of isoforms have been described

Alternatively spliced transcript variants encoding different proteins have been identified

through binding to its C-terminal region

DMPK Polyclonal Antibody, 50ul Mini dry bath The first exon of thisDystrophia myotonica protein kinase encoded by DMPK is a serine threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta subunit of the L type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5 38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50 5,000 copies causes