SPDEF Polyclonal Antibody, 100ul Recombinant Ab Production CXC receptor 2

CXC receptor 2

except in bone marrow and peripheral blood mononuclear cells

The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner

Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease

copper- and zinc- binding domains at the N-terminus

SPDEF Polyclonal Antibody, 100ul Recombinant Ab Production CXC receptor 2The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen independent transactivator of prostate specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor association than other cancer associated