MOB1(Phospho-Thr35) Rabbit Polyclonal Antibody, 100ul Bio-Reaction Tube A full-length representative protein consists

A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain

alternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-

it plays an important role in transcriptional regulation

cAMP responsive element binding protein 1 is phosphorylated by several protein kinases

and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies

MOB1(Phospho-Thr35) Rabbit Polyclonal Antibody, 100ul Bio-Reaction Tube A full-length representative protein consistsThe protein encoded by this gene is a component of the Hippo signaling pathway which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.