Mouse DNA-dependent Protein Kinase Catalytic Subunit, PRKDC ELISA Kit , 96T Molecular Sciences Promotes cell cycle progression and

Promotes cell cycle progression and tumorigenesis by down-regulating expression of a regulator of cell cycle progression

suggesting an important role in p53/TP53 stress response such as DNA damage

The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation

The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney

which are ligands for the Robo family of immunoglobulin receptors

Mouse DNA-dependent Protein Kinase Catalytic Subunit, PRKDC ELISA Kit , 96T Molecular Sciences Promotes cell cycle progression andSerine threonine protein kinase that acts as a molecular sensor for DNA damage (By similarity). Involved in DNA non homologous end joining (NHEJ) required for double strand break (DSB) repair and V(D)J recombination (By similarity). Must be bound to DNA to express its catalytic properties (By similarity). Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C) (By similarity).