Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions and age-related macular degeneration type

and age-related macular degeneration type 3 (ARMD3)

GO annotations related to this gene include receptor activity and carbohydrate binding

|tissue specificity:Expressed principally in liver

probably playing a role in regulating LPS-dependent monocyte responses

MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins

Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions and age-related macular degeneration typeThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.