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LRP5 Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Genomic sequences representing several pseudogenes

SKU: 92015224396

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LRP5 Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Genomic sequences representing several pseudogenesThis gene encodes a transmembrane low density lipoprotein receptor that binds and internalizes ligands in the process of receptor mediated endocytosis. This protein also acts as a co receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related

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Description

Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene

which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD

Orexin A and orexin B

The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene

The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes

LRP5 Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Genomic sequences representing several pseudogenesThis gene encodes a transmembrane low density lipoprotein receptor that binds and internalizes ligands in the process of receptor mediated endocytosis. This protein also acts as a co receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related

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