SEP11 Polyclonal Antibody, 50ul Micro Centrifuge Tubes It exists in both a

It exists in both a cytosolic form and an N-terminal extended form

Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells

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The mouse homolog of the protein encoded by CBLN4 competes with netrin to bind to the deleted in colorectal cancer receptor

Diseases associated with SHC3 include sclerosing hepatic carcinoma

SEP11 Polyclonal Antibody, 50ul Micro Centrifuge Tubes It exists in both aSEPT11 belongs to the conserved septin family of filament forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004