RAB3IP Polyclonal Antibody, 50ul PCR Series a cause of Zellweger syndrome

a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD)

and COA to ensure the highest quality

Mutations in this gene have been associated with invasive breast cancers

All three variant forms have similar nucleoside transport activity

Rab family

RAB3IP Polyclonal Antibody, 50ul PCR Series a cause of Zellweger syndromeGuanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP bound Rab proteins into their active GTP bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42