NCoA-3 Monoclonal Antibody, 100ul Thermo Mix An important paralog of PRAF2

An important paralog of PRAF2 is ARL6IP5

The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases

The encoded protein may play a role in apoptosis in a caspase-dependent manner

Intracellularly

This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT

NCoA-3 Monoclonal Antibody, 100ul Thermo Mix An important paralog of PRAF2The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several