MSH2 Polyclonal Antibody, 50ul Electrophoresis & Labeling APOOL encodes apolipoprotein O like

APOOL encodes apolipoprotein O like which contains an apolipoprotein O superfamily domain

This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system

Grp78 and following heat shock

Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome

Activated by phosphorylation on Thr-211 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

MSH2 Polyclonal Antibody, 50ul Electrophoresis & Labeling APOOL encodes apolipoprotein O likeMSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.