IRP-1(Phospho Ser711) Polyclonal Antibody, 100ul Drug Development and Evaluation Studies of FLASH protein suggested

Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor

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which is found to encode an expanded glutamine tract in cases of Huntington's disease

Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene

IRP-1(Phospho Ser711) Polyclonal Antibody, 100ul Drug Development and Evaluation Studies of FLASH protein suggestedThe protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe 4S cluster and functions as an aconitase. Aconitases are iron sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds