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AGRIN Polyclonal Antibody, 20ul 3D Cell Culture Consumables the light chain contains 2

SKU: 94463057252

4.0
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AGRIN Polyclonal Antibody, 20ul 3D Cell Culture Consumables the light chain contains 2This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ) as identified in mouse knock out studies. The encoded protein contains several laminin G Kazal type serine protease inhibitor and epidermal growth factor domains. Additional post translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb girdle muscles

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Description

the light chain contains 2 EGF-like domains

In a non-canonical activation pathway| the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB| inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes

The smooth muscle α-actin and γ-actin proteins are found primarily in vascular smooth muscle and enteric smooth muscle

May be a component of the chromosomal passenger complex (CPC)

This protein is commonly used as a biomarker of neuronal damage

AGRIN Polyclonal Antibody, 20ul 3D Cell Culture Consumables the light chain contains 2This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ) as identified in mouse knock out studies. The encoded protein contains several laminin G Kazal type serine protease inhibitor and epidermal growth factor domains. Additional post translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb girdle muscles

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