ALS2 Polyclonal Antibody, 50ul Variant Libraries Max-binding protein MNT is likely

Max-binding protein MNT is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth

Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19

it plays an important role in transcriptional regulation

Isoform 1 is the lowest abundant in the blood

subunit:Interacts with SH3GL1/endophilin-2

ALS2 Polyclonal Antibody, 50ul Variant Libraries Max-binding protein MNT is likelyThe protein encoded by this gene contains an ATS1 RCC1 like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics.