Tuberin/TSC2(Phospho-Ser1387) Rabbit Polyclonal Antibody, 20ul Mini dry bath an Arf-GAP domain

an Arf-GAP domain

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B)

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

beta (IL10BR/CRFB4)

This protein is essential for the folding and assembly of newly imported proteins in the mitochondria

Tuberin/TSC2(Phospho-Ser1387) Rabbit Polyclonal Antibody, 20ul Mini dry bath an Arf-GAP domainMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.