PAX3 Polyclonal Antibody, 100ul 3D Cell Culture Consumables and autosomal recessive non-syndromic sensorineural

and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53)

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes

The expression of this DNA binding protein is upregulated by transcription factor p53

which is a homolog of VASA proteins in Drosophila and several other species

expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts

PAX3 Polyclonal Antibody, 100ul 3D Cell Culture Consumables and autosomal recessive non-syndromic sensorineuralThis gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial deafness hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2; 13)(q35; q14), which represents a fusion between PAX3 and