Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment subunit:Binds the second PAH repeat

subunit:Binds the second PAH repeat of SIN3A (By similarity)

CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail

it is normally found in the nucleus except during mitosis

|enzyme regulation:Specifically inhibited by the intercalating agent amsacrine

tissue specificity:Expression largely restricted to adipose tissue and spleen

Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment subunit:Binds the second PAH repeatEndosomal receptor that plays a key role in innate and adaptive immunity (PubMed: 14976261, PubMed: 32433612). Controls host immune response against pathogens through recognition of uridine containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs (PubMed: 31608988, PubMed: 27742543, PubMed: 12738885). Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the