GATA-1 Polyclonal Antibody, 50ul[BT-AP03480] Peripheral Blood Separation Tube The protein encoded by HAT1

The protein encoded by HAT1 (histone acetyltransferase 1)is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones

The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling

Numerous pseudogenes have been reported for this gene

Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity

Mutations in CCND2 are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3)

GATA-1 Polyclonal Antibody, 50ul[BT-AP03480] Peripheral Blood Separation Tube The protein encoded by HAT1GATA1 encodes Erythroid transcription factor which belongs to the GATA family of transcription factors. Erythroid transcription factor plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in GATA1 have been associated with X linked dyserythropoietic anemia and thrombocytopenia.