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STAM2(Phospho Tyr192) Polyclonal Antibody, 50ul Culture Media Five variable segments can be

SKU: 96019581318

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STAM2(Phospho Tyr192) Polyclonal Antibody, 50ul Culture Media Five variable segments can beThe protein encoded by this gene is closely related to STAM an adaptor protein involved in the downstream signaling of cytokine receptors both of which contain a SH3 domain and the immunoreceptor tyrosine based activation motif (ITAM). Similar to STAM this protein acts downstream of JAK kinases and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway

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Description

Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols

Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation

suggesting that it has no protease activity

FLRTs may function in cell adhesion and/or receptor signalling

STAM2(Phospho Tyr192) Polyclonal Antibody, 50ul Culture Media Five variable segments can beThe protein encoded by this gene is closely related to STAM an adaptor protein involved in the downstream signaling of cytokine receptors both of which contain a SH3 domain and the immunoreceptor tyrosine based activation motif (ITAM). Similar to STAM this protein acts downstream of JAK kinases and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway

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