CL18A Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator Angelman syndrome

Angelman syndrome

Three transcript variants encoding two different isoforms have been found for TRAF1

also known as WDR94 or KIAA1736

30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT

since either subunit alone results in receptors with very low conductance and response amplitude

CL18A Rabbit Polyclonal Antibody, 100ul Vacuum Aspirator Angelman syndromeThis is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C type lectin domains. These domains bind to carbohydrates in the presence of calcium and may be involved in cell adhesion immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.