PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes It is involved in mammalian

It is involved in mammalian pigmentation

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The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine

A related pseudogene has been identified on chromosome 4

May be involved in apoptosis signaling in the presence of the reinoid CD437

PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes It is involved in mammalianCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001