HSF4 Polyclonal Antibody, 100ul Human Genome Knockout Libraries Diseases associated with SRCIN1 include

Diseases associated with SRCIN1 include sclerosing keratitis and loiasis

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase

which may be required for its phosphorylation

Note that CLK2 is distinct from the TELO2 gene (GeneID:9894)

and plays a role during the calcification of cartilage and the transition of cartilage to bone

HSF4 Polyclonal Antibody, 100ul Human Genome Knockout Libraries Diseases associated with SRCIN1 includeHeat shock transcription factors (HSFs) activate heat shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.