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Cot(Phospho Ser400) Polyclonal Antibody, 20ul Cryogenic Vials Mutations in this gene result

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Cot(Phospho Ser400) Polyclonal Antibody, 20ul Cryogenic Vials Mutations in this gene resultThis gene is an oncogene that encodes a member of the serine threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF kappaB. This protein was also found to promote the production of TNF alpha and IL 2 during T lymphocyte activation. This gene may also utilize a downstream

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Description

Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy

The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains

are specific from viruses

In combination with the beta 7 integrin

which houses over 1

Cot(Phospho Ser400) Polyclonal Antibody, 20ul Cryogenic Vials Mutations in this gene resultThis gene is an oncogene that encodes a member of the serine threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF kappaB. This protein was also found to promote the production of TNF alpha and IL 2 during T lymphocyte activation. This gene may also utilize a downstream

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