MMAC Rabbit Polyclonal Antibody, 100ul Fluorescent Staining Mothers against decapentaplegic homolog 1

Mothers against decapentaplegic homolog 1 encoded by SMAD1 belongs to the SMAD

|PTM:Acetylation by CBP| which is induced by peroxidase stress| inhibits transcriptional activity

is one of several HOXC genes located in a cluster on chromosome 12

This protein may have a proliferative effect and play a role in cancer development or progression

GO annotations related to this gene include peptidase activity and aminopeptidase activity

MMAC Rabbit Polyclonal Antibody, 100ul Fluorescent Staining Mothers against decapentaplegic homolog 1The exact function of the protein encoded by this gene is not known however its C terminal region shows similarity to TonB a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.