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MIB2 Polyclonal Antibody, 20ul Centrifugal Filter Other transcription factors that interact

SKU: 9827456634

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MIB2 Polyclonal Antibody, 20ul Centrifugal Filter Other transcription factors that interactE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result

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Description

Other transcription factors that interact with this protein are signal transducers and activators of transcription

Multiple transcript variants encoding different isoforms have been found for PHF1

an N-linked glycan-processing enzyme in the endoplasmic reticulum

and play a role in several developmental processes including early embryonic cell fate and organogenesis

and retinoblastoma-like protein 2 (RBL2

MIB2 Polyclonal Antibody, 20ul Centrifugal Filter Other transcription factors that interactE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result

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