CCAR1 Polyclonal Antibody, 20ul Yeast Expression CBL has been found to

CBL has been found to be mutated or translocated in many cancers including acute myeloid leukaemia

This gene may also play a role in tumor progression

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family

SCNN1G encodes the gamma subunit

CCAR1 Polyclonal Antibody, 20ul Yeast Expression CBL has been found toMay be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14 3 3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and or cell proliferation.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 SAP