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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Mutations in this gene are

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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Mutations in this gene areThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN)

Neurofibromatosis type 2

Inflammatory stimuli can induce IKK-mediated phosphorylation of PIAS1 at Ser90

COL2A1 encodes the alpha-1 chain of type II collagen

Synapsin-1 encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal

p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Mutations in this gene areThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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